CJC-1295 5mg UK (No DAC / MOD GRF 1-29)
This is CJC-1295 without DAC. The same compound is also sold as MOD GRF 1-29. If you are looking for CJC-1295 with drug affinity complex (the long-acting version), see our CJC-1295 with DAC 5mg or 10mg options.
What is the difference between CJC-1295 with and without DAC?
Both products contain the same modified GRF 1-29 peptide sequence with four substitutions (Ala2, Ala8, Ala15, Leu27) that protect it from DPP-IV enzymatic degradation. The difference is a chemical addition called a Drug Affinity Complex (DAC).
| Version | CJC-1295 without DAC (this product) | CJC-1295 with DAC |
| Half-life | ~30 minutes | 6-8 days |
| GH release pattern | Pulsatile (physiological) | Sustained elevation |
| Best used for | Mimicking natural GH pulses | Continuous GHRH-R activation studies |
| Typical pairing | Pairs with Ipamorelin or GHRP-2 | Used standalone in research |
Product Specifications
| Molecular Formula | C165H269N47O46 |
| Molecular Weight | 3,367.97 g/mol |
| CAS Number | 863288-34-0 |
| Amino Acids | 29 (modified GHRH 1-29) |
| Purity | ≥99% (HPLC & MS verified) |
| Form | White lyophilised powder |
Research Applications
CJC-1295 (no DAC) is studied as a selective GHRH receptor agonist. It activates the same receptor as endogenous growth hormone releasing hormone, triggering pulsatile GH release from pituitary somatotrophs. The four amino acid substitutions extend the functional half-life from about 7 minutes (native GHRH) to roughly 30 minutes, which is long enough to produce a full GH pulse but short enough to preserve physiological rhythm.
The most commonly studied research protocol pairs CJC-1295 (no DAC) with a GHS-R agonist such as Ipamorelin or GHRP-2. This dual activation produces synergistic GH release that is greater than either pathway alone. For convenience, we also stock pre-combined blends: Ipamorelin + MOD GRF blend and GHRP-2 + MOD GRF blend.
Frequently Asked Questions
What is DAC in CJC-1295?
DAC stands for Drug Affinity Complex, a reactive maleimide group added to the peptide that forms a covalent bond with serum albumin. This albumin binding creates a circulating reservoir, extending the half-life from 30 minutes to 6-8 days. The DAC version produces sustained GH elevation; the non-DAC version (this product) produces pulsatile GH release.
Is CJC-1295 legal to buy in the UK?
CJC-1295 is sold in the UK strictly as a research chemical for laboratory use, not for human consumption. It is not licensed as a medicine in the UK. Purchasers are responsible for complying with all applicable regulations.
How do I reconstitute CJC-1295 5mg?
Typically reconstituted with 2ml of bacteriostatic water for a concentration of 2.5 mg/ml. Full guide: How to Reconstitute Peptides.
For research and laboratory use only. Not for human or veterinary consumption.




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