GHK-Cu 50 mg — Research-Grade Copper Peptide
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring tripeptide-copper complex first identified in human plasma. Present at concentrations of approximately 200 ng/ml in young adults — declining significantly with age — GHK-Cu has emerged as one of the most studied peptides in skin biology, tissue remodelling, and ageing research.
The copper ion is integral to GHK-Cu’s biological activity. The GHK tripeptide acts as a carrier that delivers copper to cellular targets, where it participates in enzymatic reactions critical to collagen cross-linking, antioxidant defence, and gene expression modulation.
Product Specifications
| Product Name | GHK-Cu Copper Peptide 50 mg |
| Molecular Formula | C₁₄H₂₄CuN₆O₄ |
| Molecular Weight | 403.92 g/mol |
| CAS Number | 49557-75-7 |
| Sequence | Gly-His-Lys · Cu²⁺ |
| Purity | ≥99% (HPLC & MS verified) |
| Form | Blue-tinged lyophilised powder |
| Solubility | Freely water-soluble |
| Solution Appearance | Blue tint (normal — from copper ion) |
| Storage | -20°C (lyophilised) · 2–8°C (reconstituted) |
Research Background
GHK-Cu’s research profile spans three major areas:
Collagen and extracellular matrix remodelling — GHK-Cu has been shown to stimulate collagen type I, III, and V synthesis, increase decorin and glycosaminoglycan production, and promote the activity of matrix metalloproteinases (MMPs) involved in tissue remodelling. These effects are central to wound healing and skin biology research.
Gene expression modulation — Broad-spectrum gene array studies have identified over 4,000 genes whose expression is modulated by GHK-Cu, including genes involved in antioxidant defence, DNA repair, ubiquitin-proteasome pathways, and stem cell biology. This unusually wide-ranging activity profile has driven significant interest in ageing and longevity research.
Antioxidant and anti-inflammatory activity — GHK-Cu has been studied for its ability to reduce oxidative damage markers, modulate inflammatory cytokine expression (particularly IL-6 and TNF-α), and support cellular resilience under stress conditions.
Reconstitution
Reconstitute with bacteriostatic water. GHK-Cu dissolves readily — the reconstituted solution will have a characteristic blue tint from the copper ion. This is entirely normal and indicates the copper complex is intact. Full guide: How to Reconstitute Peptides.
Related Products
GHK-Cu pairs well with Epithalon in ageing and longevity research protocols — we offer a pre-mixed GHK-Cu + Epithalon Blend. Also available: Matrixyl and SNAP-8 for skin biology research. Browse Anti-Ageing & Longevity or Skin & Tanning.
All products sold by BioLab Peptides are intended strictly for laboratory and research purposes. Not for human or veterinary consumption.




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