Fragment 176-191 5 mg – GH Lipolytic Fragment
Fragment 176-191 is the C-terminal 16-amino-acid segment of human growth hormone, isolated specifically for its fat-metabolising properties. This fragment retains the lipolytic activity of full-length GH without its growth-promoting, IGF-1-elevating, or diabetogenic effects, making it a targeted tool for lipid metabolism research.
Research Background
Isolated lipolytic activity – Fragment 176-191 stimulates lipolysis (fat breakdown) and inhibits lipogenesis (fat formation) in adipose tissue models. Critically, it does not bind the GH receptor in the same way as full-length GH, so it does not elevate IGF-1 or affect glucose homeostasis.
Comparison with AOD-9604Â –Â AOD-9604Â is a modified version of Fragment 176-191 with an additional N-terminal tyrosine residue. Both are studied for lipolytic activity, but AOD-9604 has additional published data on cartilage and bone research applications.
Weight management research – The fragment’s ability to target fat metabolism without systemic GH effects makes it valuable in metabolic research protocols focused specifically on adipose tissue biology.
Related Products
Also available as Fragment 176-191 Spray. See also AOD-9604, 5-Amino-1MQ, and the pre-mixed Fragment + MOD GRF + Ipamorelin Blend. Browse Weight Management.



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