DSIP 5 mg – Delta Sleep Inducing Peptide
DSIP (Delta Sleep Inducing Peptide) is a naturally occurring nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) first identified in 1977 from cerebral venous blood of rabbits during induced sleep. Unlike conventional sedatives, DSIP does not force sleep but appears to modulate the architecture and quality of natural sleep patterns, making it a unique tool for chronobiology and sleep research.
Product Specifications
| Molecular Formula | C35H48N10O15 |
| Molecular Weight | 848.81 g/mol |
| CAS | 62568-57-4 |
| Purity | ≥99% (HPLC & MS) |
Research Background
Sleep architecture modulation – DSIP has been studied for its effects on delta-wave (slow-wave) sleep, the deepest and most restorative phase of the sleep cycle. Rather than acting as a sedative, it appears to promote the natural transition into and maintenance of deep sleep stages.
Stress and cortisol – Research indicates DSIP may modulate the hypothalamic-pituitary-adrenal (HPA) axis, with studies reporting effects on cortisol rhythms and stress-response adaptation. This has positioned it as a research compound at the intersection of sleep and stress biology.
Opioid system interaction – Some studies suggest DSIP influences endogenous opioid systems, potentially affecting pain perception and withdrawal models, though the precise receptor interactions remain under investigation.
Reconstitution and Related Products
Reconstitute with 1-2 ml of bacteriostatic water. Also available as DSIP Nasal Spray. For complementary sleep and stress research, see Selank (anxiolytic). Browse Cognitive & Nootropic. Guide: How to Reconstitute Peptides.




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