Epithalon 10 mg

Epithalon 10mg UK (also spelled Epitalon)

Epithalon, also commonly spelled Epitalon or Epithalamin, is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology. It is the synthetic version of Epithalamin, a natural pineal gland extract, and is one of the most extensively studied peptides in longevity and chronobiology research.

Product Specifications

Research Background

Telomerase activation. Epithalon is most recognised in research for its studied effect on telomerase enzyme activity. Published studies from the Khavinson group and others have reported Epithalon’s ability to activate telomerase in somatic cells that normally do not express the enzyme, leading to telomere elongation in cultured fibroblasts and lymphocytes.

Pineal gland bioregulation. Epithalon is the short peptide bioregulator associated with the pineal gland. It has been studied for effects on melatonin rhythm normalisation, circadian function, and cortisol regulation, particularly in ageing models where pineal function declines.

Longevity studies. Long-term animal studies by Khavinson and colleagues have investigated Epithalon’s effects on lifespan, age-related morbidity, and tumour incidence in multiple rodent models. These studies contributed to the broader bioregulation theory of ageing.

Gene expression modulation. Short peptide bioregulators including Epithalon are proposed to bind directly to gene promoter regions, modulating transcription of specific genes associated with their tissue of origin. Published research describes chromatin-level effects distinct from conventional receptor-mediated peptide signalling.

Reconstitution & Related Products

Reconstitute with 2ml of bacteriostatic water for a concentration of 5 mg/ml. Full guide: How to Reconstitute Peptides.

Also available as Epithalon Nasal Spray and enhanced N-Acetyl Epithalon (improved stability). For complementary longevity research, see SS-31, MOTS-c, and FOX04-DRI. Browse Anti-Ageing & Longevity.

Frequently Asked Questions

Is it spelled Epithalon or Epitalon?
Both spellings refer to the same peptide. “Epithalon” is the more common English transliteration; “Epitalon” appears in Russian and Eastern European scientific literature. The compound is identical: Ala-Glu-Asp-Gly.

What is Epithalon’s mechanism?
Epithalon is primarily studied for telomerase enzyme activation and pineal bioregulation. It is categorised as a short peptide bioregulator in the Khavinson classification system, proposed to interact with DNA at the chromatin level to modulate gene expression.

Is Epithalon legal to buy in the UK?
Epithalon is sold as a research chemical in the UK for laboratory use only. It is not a licensed medicine and is not intended for human or veterinary consumption.

For research and laboratory use only. Not for human or veterinary consumption.