Melanotan 2 10 mg | Melanocortin Research Peptide
Melanotan 2 (MT-2) is a synthetic cyclic analogue of α-melanocyte stimulating hormone (α-MSH), originally developed at the University of Arizona. As a non-selective melanocortin receptor agonist, it activates MC1R through MC5R — making it a broad research tool for melanocortin pathway biology.
Product Specifications
| Molecular Weight | 1,024.18 g/mol |
| CAS | 121062-08-6 |
| Sequence | Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂ |
| Purity | ≥99% (HPLC & MS) |
Research Background
Melanogenesis (MC1R) — MT-2’s activation of melanocortin-1 receptor stimulates melanin synthesis in melanocytes, driving research into skin pigmentation biology, UV-protection mechanisms, and melanocyte signalling.
Sexual function (MC3R/MC4R) — MT-2’s non-selective profile means it also activates the same hypothalamic melanocortin receptors studied with PT-141, making it useful for comparative melanocortin pathway research.
Appetite and energy homeostasis (MC4R) — The melanocortin-4 receptor is a key regulator of energy balance. MT-2’s agonist activity at MC4R has been studied in appetite regulation and metabolic research models.
Related Products
Also available as Melanotan 2 Spray. See also PT-141 (selective derivative) and GHK-Cu for skin biology research. Browse Skin & Tanning.
For research use only. Not for human or veterinary consumption.




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