Buy Sermorelin 2mg UK – GHRH (1-29) Research Peptide
Sermorelin is a synthetic 29-amino-acid peptide identical to the first 29 amino acids of endogenous GHRH (growth hormone releasing hormone). This truncated fragment retains full biological activity at the GHRH receptor. It is the shortest fragment of GHRH that maintains complete receptor affinity and GH-releasing potency.
Product Specifications
| Product Name | Sermorelin 2mg (Sermorelin acetate) |
| Other names | GRF 1-29, GRF 1-29 NH2, Sermorelin acetate |
| Molecular Weight | 3,357.89 g/mol |
| CAS Number | 86168-78-7 |
| Amino Acids | 29 (GHRH 1-29) |
| Purity | ≥99% (HPLC & MS) |
| Form | White lyophilised powder |
Research Background
Physiological GH stimulation. Sermorelin stimulates pulsatile GH release through GHRH receptor activation on pituitary somatotrophs. Unlike exogenous GH, it preserves the natural negative feedback loop, which makes it a more physiologically relevant tool for GH-axis research than direct GH administration.
Ageing research. GH secretion declines with age (the phenomenon known as somatopause). Sermorelin is studied as a research tool for investigating age-related changes in the GH/IGF-1 axis and their downstream effects on body composition, sleep architecture, and metabolic parameters.
Comparison with CJC-1295. Both Sermorelin and CJC-1295 (MOD GRF 1-29) activate the GHRH receptor. CJC-1295 has four amino acid substitutions for DPP-IV resistance, giving it a longer half-life than Sermorelin. Sermorelin’s shorter duration allows tighter research control of GH pulse timing.
Sermorelin Research: What Questions Are Researchers Asking?
Is Sermorelin the same as Sermorelin acetate?
Yes. The acetate is the counterion used in the standard lyophilised salt form of the peptide. The active peptide is identical.
Is Sermorelin legal to buy in the UK?
Sermorelin is sold in the UK as a research chemical for laboratory use only. It is not licensed as a medicine in the UK (it is, however, available as a prescription medicine in some other jurisdictions including the US). UK sales are for research purposes, not for human or veterinary consumption.
What is the typical Sermorelin research protocol?
Published protocols typically use Sermorelin in combination with a GHS-R agonist (such as Ipamorelin) to produce synergistic GH release. The 2mg vial is the standard supply format and is reconstituted with bacteriostatic water per laboratory protocol.
How much does Sermorelin cost in the UK?
See current pricing displayed on this product page. We typically position Sermorelin at the standard research-grade price point for 2mg vials, with full Certificate of Analysis included.
Related Products
Compare with CJC-1295 (MOD GRF 1-29) which is the DPP-IV-resistant variant with longer half-life. For synergistic protocols, see Ipamorelin and GHRP-2. Pre-mixed blends: Ipamorelin + MOD GRF and GHRP-2 + MOD GRF. Browse Growth Hormone Secretagogues.
For research and laboratory use only. Not for human or veterinary consumption.




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